Lily Allen and Pixie Lott also in the running
The US singer, 23, real name Stefani Germanotta, has been nominated for Best International Female, Breakthrough Artist and Best Album.
JLS are up for Best British Group, British Breakthrough Act and Best British Single for Beat Again.
Other nominees include Robbie Williams, who is to be honoured with the Outstanding Contribution To Music Award, for Best British Male.
The Brits take place at London’s Earls Court Arena on 16 February.
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